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Review | Regular issue | Vol 106, No. 9, 2023, pp.1478-1513
Published online, 9th June, 2023
DOI: 10.3987/REV-23-1010
Thiofunctionalized γ-Lactams

Alla I. Vaskevych* and Mykhailo Vovk

*Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Academician Kukhar Str., 5, Kyiv-94, 02660, Ukraine


This review summarizes and analyzes literature data concerning the methods of preparation and some aspects of synthetic and biomedical applications of 3-, 4-, and 5-thiosubstituted γ-lactams. The material is systematized for each type of structure according to the prevalence and importance of synthetic methods. Practical application aspects are combined in a section that includes all types of compounds. The bibliography of the review involves 120 sources, from the appearance of the first publications till now.