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Review | Regular issue | Vol 106, No. 9, 2023, pp.1443-1477
Published online, 14th June, 2023
DOI: 10.3987/REV-23-1009
Recent Trends in the Synthesis of Enaminones

Al-Shimaa Badran, Najla A. Alshaye, Zeinab Hussain,* Aya Ahmed, and Magdy A. Ibrahim

*Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Heliopolis 11757, Cairo, Egypt


Enaminones are very useful intermediates for building different categories of heterocyclic compounds. Formation of enaminone derivatives was achieved using a variety of compounds such as alcohols, aldehydes, active methyl ketones, active methylene ketones, β-alkoxy ketones, β-diketones, acetoacetamides, Grignard reagents, diazocarbonyl compounds, acetylene derivatives, nitrile derivatives, cyclic compounds, acyl chloride and other enaminones. The present review covers the methods developed for the synthesis of enaminone derivatives.