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■ Diterpenoid Alkaloids from Aconitum elliotii Lauener

Ziyu Zhang, Yan Xiao, Peixin Deng, Lin Chen, Shuai Huang, Mengyi Deng, and Xianli Zhou*

*School of Life Science and Engineering, Southwest Jiaotong University, NO.111, North Second Ring Road Chengdu 610031, Sichuan, China

Abstract

Three new diterpenoid alkaloids (1–3), which were named elliotitine A (1), 8-O-ethylindaconitine (2) and 8-O-ethylbikhaconine (3), along with thirty-three known compounds, were isolated from the roots of Aconitum elliotii Lauener. Their structures were elucidated via HR-ESI-MS, 1D and 2D NMR, and X-ray data. Additionally, the anti-inflammation activities of all compounds were evaluated, no compound showed significant anti-inflammatory activity.