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Short Paper | Regular issue | Vol 106, No. 2, 2023, pp.346-357
Published online, 19th December, 2022
DOI: 10.3987/COM-22-14791
Concise Formal Synthesis on Solandelactone E Based on a Regioselective Cyclopropanation

Norihiko Kawasaki, Yu Kikuoka, Keita Komine, Hayato Fukuda, and Jun Ishihara*

*Pharmaceutical Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan


A concise synthetic approach to solandelactone E has been developed based on a regio- and stereoselective cyclopropanation using Zn(CH2I)2·DME and butyldioxaborolane.