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Short Paper | Regular issue | Vol 104, No. 3, 2022, pp.549-555
Published online, 8th December, 2021
DOI: 10.3987/COM-21-14587
A New Iridoid Glycoside from Santisukia pagetii

Poolsak Sahakitpichan, Nitirat Chimnoi, Chutima Srinroch, Chaleaw Petchthong, Somsak Ruchirawat, and Tripetch Kanchanapoom*

*Chulabhorn Research Institute, Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand


A new iridoid glycoside, 6-O-[(2E,6R)-8-hydroxy-2,6-dimethyl-2-octenoyl]-catalpol (kanchanikoside, 1) was isolated from the leaves and twigs of Santisukia pagetii. In addition to the new compound, the 17 known glycosides were isolated: nemoroside, 6"(Z)-nemoroside, ambiguuside, specioside, verminoside, 6-trans-feruloylcatalpol, 6,6'-di-O-caffeoylcatalpol, amphicoside, 6-O-veratroylcatalpol, citrusin B, (7R,8S)-balanophonin 4-O-β-D-glucopyranoside, (7R,8S)-dehydrodiconiferyl-O-β-D-glucopyranoside, martynoside, benzyl O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside, benzyl O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside, icariside D1 and (6S,9R)-roseoside. Their structures were determined based on the spectroscopic evidence including 1D and 2D NMR, and HR-ESI-TOF-MS experiments.