Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 102, No. 7, 2021, pp.1330-1336
Published online, 3rd June, 2021
DOI: 10.3987/COM-21-14462
A New Denudatine Type C20-Diterpenoid Alkaloid from Aconitum fischeri var. arcuatum

Lili Qin, Feng Xing, Lin Chen,* and Xianli Zhou*

*School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, People’s Republic of China


A new denudatine-type C20-diterpenoid alkaloid bearing a rare C-15 ketone carbonyl and 16,17-epoxy group, named arcutisine (1), together with 24 known compounds (2-25), were obtained from the roots of Aconitum fischeri var. arcuatum. Their structures were established by various spectroscopic analyses. Among them, compounds 1 and 2 were both isolated from a natural source for the first time. Besides, compounds 7 and 10 showed weak effect on anti-inflammatory activity with the inhibition rate of 33.5% and 33.7% at the concentration of 40 µM.