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Paper | Regular issue | Vol 100, No. 12, 2020, pp.2072-2082
Published online, 26th October, 2020
DOI: 10.3987/COM-20-14350
Montmorillonite K-10 Catalyzed Microwave-Assisted Synthesis of Pyrroles in Solvent Free Conditions

Chaowei Ma* and Guosheng Huang

*College of Chemistry and Environmental Engineering, Xinjiang Institute of Engineering, Xinjiang Wulumuqi Nanchang Road 830091, china


An effective microwave-induced, montmorillonite K-10 catalyzed, environmentally benign synthesis of substituted pyrroles from α‑amino carbonyl compounds and aldehydes under solvent-free conditions is described. The reaction involving various substituted substrates proceeds smoothly, and substituted pyrroles are synthesized in moderate to excellent yields within minutes. The developed method offers advantages such as operational simplicity, solvent-free, rapid reaction rate and use of a commercially recyclable catalyst.