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Review | Regular issue | Vol 102, No. 4, 2021, pp.583-621
Published online, 6th October, 2020
DOI: 10.3987/REV-20-941
Synthetic Methods for Phosphorus Compounds Containing Chromone and Thiochromone Rings

Tarik E. Ali,* Mohammed A. Assiri, Somaia M. Abdel-Kariem, and Ibrahim S. Yahia

*Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt


The chromone and thiochromone rings are prominent heterocyclic substructures present in numerous natural and pharmacologically active compounds. To date, many chromone analogues containing phosphorus compounds are interest in several laboratories due to their potent pharmacological activities. This review compiles all the available literature data on the synthesis of phosphorus compounds containing chromone and thiochromone rings as well as their available biological properties starting from their appearance up to the end of 2019.