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Short Paper | Regular issue | Vol 100, No. 10, 2020, pp.1678-1685
Published online, 20th August, 2020
DOI: 10.3987/COM-20-14315
Amphirionins-3 and -6, New Polyketides from the Cultured Marine Dinoflagellate Amphidinium Species

Masashi Tsuda,* Ryui Makihara, Mika Minamida, Masayuki Tsuda, Mai Akakabe, Keiko Kumagai, Eri Fukushi, Jun Kawabata, and Takeyuki Suzuki

*Center for Advanced Marine Core Research , Kochi University, Nankoku, Kochi 783-8502, Japan


Amphirionins-3 (1) and -6 (2) have been isolated from the marine dinoflagellate Amphidinium species. The structures were elucidated by detail analyses of the spectroscopic data, and chemical conversions. Compounds 1 and 2 exhibited moderate cytotoxic activity against human cervix adenocarcinoma HeLa cells.