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Paper | Regular issue | Vol 100, No. 7, 2020, pp.1035-1047
Published online, 28th May, 2020
DOI: 10.3987/COM-20-14264
Synthesis, Characterization and Antimicrobial Evaluation of Some Novel Chromenopyridine, Pyranochromene and 3-Hetarylcoumarin Derivatives

Khaled S. Mohamed* and Engy E. Elbialy

*Engineering Chemistry Department, Higher Institute for Engineering and Technology, New Damietta, New Damietta 34518, Egypt

Abstract

3-Acetylcoumarin was used as a precursor for the synthesis of novel fused heterocyclic compounds as chromeno[3,4-c]pyridine, chromeno[4,3-b]pyridine and pyrano[3,4-c]chromene derivatives in addition to the synthesis of 3-hetarylchromene derivatives. The chemical structures of newly synthesized compounds were avowed by means of spectral and analysis data. The novel synthesized compounds were estimated as antibacterial agents against Staphylococcus aureus and Escherichia coli bacteria.