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Paper | Regular issue | Vol 98, No. 11, 2019, pp.1513-1524
Published online, 6th November, 2019
DOI: 10.3987/COM-19-14167
A Highly Selective Fluorescence-Enhanced Probe for the Rapid Detection of SO2 Derivatives and Its Bio-Imaging in Living Cells

Yaogen Zhou, Yiwei Zhou, Hongying Wang,* and Baoquan Chen*

*School of Chemistry and Chemical Engineering, Tianjin University of Technology, 391 Binshui Xidao, Xiqing District Tianjin 300384, China


In this study, we report a simple coumarin-based probe CISD for the detection of SO2 derivatives. In the case of the probe CISD, HSO3 can induce an obvious fluorescence-enhanced response with high selectivity, fast response (within 10 sec) as well as low limit of detection (262 nM). HR-MS experiment revealed the sensing mechanism concerning the nucleophilic addition reaction. Furthermore, the probe CISD has been successfully applied for imaging exogenous HSO3 in living HeLa cells.