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Paper | Regular issue | Vol 98, No. 8, 2019, pp.1089-1103
Published online, 15th August, 2019
DOI: 10.3987/COM-19-14134
Synthesis and Antioxidant Activities of Some Novel Indane-Amide Substituted Pyrazole, Pyrimidine, Pyridine and 2-Pyrone Derivatives

Khaled S. Mohamed* and Elsherbiny H. El-Sayed

*Engineering Chemistry Department, Higher Institute for Engineering and Technology, New Damietta, New Damietta 34518, Egypt


2-Cyano-N-(2,3-dihydro-1H-5-indenyl)-3-(dimethylamino)acrylamide (3) was used in synthetic paths to some novel indane-amide containing pyrazole, pyrimidine, fused pyrimidines, fused pyridines and 2-pyrone derivatives by reaction of 3 with various reagents. The newly synthesized compounds were investigated for their antioxidant activity. Some of the tested compounds exposed auspicious activities.