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Paper | Regular issue | Vol 98, No. 2, 2019, pp.236-270
Published online, 13th February, 2019
DOI: 10.3987/COM-19-14031
Synthesis of 1-Methoxyindoles and Related Analogs of Pimprinine, (±)-Chelonin A and B, Based on 1-Hydroxyindole Chemistry

Kazuko Aoki, Yoshiyuki Nagahama, Katsuko Sugaya, Yuki Maeda, Haruhiko Sato, Kyoko Nakagawa (Goto), and Masanori Somei*

*Noto Marine Laboratory, Institute of Nature and Environmental Technology, Faculty of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, 56-7 Matsuhidai, Matsudo-shi, Chiba 270-2214, Japan

Abstract

The total synthesis of pimprinine, (±)-chelonin A and B, and their analogs are achieved based on 1-hydroxyindole chemistry.