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Short Paper | Regular issue | Vol 98, No. 1, 2019, pp.114-125
Published online, 22nd January, 2019
DOI: 10.3987/COM-18-14020
4,6-Diacetylresorcinol in Heterocyclic Synthesis Part II: Synthesis of Some Novel 4,6-Bis(azolyl/azinyl/azepinyl)resorcinols

Mohammed A. Assiri, Tarik E. Ali,* Magdy A. Ibrahim, E. M. El-Amin, and I. S. Yahia

*Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt


A series of new 4,6-bis(azolyl/azinyl/azepinyl)resorcinols was synthesized in a combinatorial manner besides, (2E,2'E)-4,6-bis[3-(aminophenyl-substituted)prop-2-en-1-oxo-1-yl]resorcinols were also obtained. Heterocyclization of (2E,2'E)-4,6-bis[3-(dimethylamino)prop-2-en-1-oxo-1-yl]resorcinol (2) with nitrogen-containing binucleophiles afforded the target compounds. All the newly synthesized compounds were characterized by spectral tools.