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Paper | Regular issue | Vol 96, No. 10, 2018, pp.1729-1739
Published online, 26th October, 2018
DOI: 10.3987/COM-18-13957
Microwave Promoted Diels-Alder Reaction of 1,2-Dihydropyridine

Stephen R. Slauson,* Natalia Echeverry, Samantha Copeland, Alessandra Stoj, Melissa A. Kemp, and Maria Simon

*Department of Pharmaceutical Sciences, School of Pharmacy, University of Saint Joseph, 229 Trumbull Street, Hartford, CT 06103, U.S.A.


The microwave-assisted Diels-Alder reaction between 1,2-dihydropyridine and activated dienophiles is reported. The conditions facilitate the production of the [2.2.2] scaffold in high yields with simple purification.