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Obituary
Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Short Paper | Regular issue | Vol 96, No. 3, 2018, pp.501-508
Published online, 2nd March, 2018
Published online, 2nd March, 2018
DOI: 10.3987/COM-18-13867
■ Brønsted Acid-Promoted Multicomponent Reaction for the Construction of Pyrrolocoumarin Derivatives
Zhiwei Chen,* Sunjia Ye, and Xiongfei Zhang
*Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, China
Abstract
An efficient one-pot synthesis of functionalized indole-containing pyrrolocoumarin derivatives via a three-component reaction of 4-aminocoumarins, arylglyoxal monohydrates and indoles promoted by p-TSA in ethanol is described. The attractive features of this protocol are simple starting materials, operational simplicity, short reaction time and moderate to good yields.
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