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Review | Regular issue | Vol 96, No. 4, 2018, pp.595-639
Published online, 28th February, 2018
DOI: 10.3987/REV-17-879
4,5-Dihydro-1H-tetrazoles — 5-Alkyl/Aryl and 5-Alkylidene Derivatives

Dietrich Moderhack*

*Institute of Medicinal and Pharmaceutical Chemistry, Technical University, Braunschweig, Beethovenstrasse 55, D-38106, Germany


Nine types of 5-alkyl/aryl- and 5-alkylidene-4,5-dihydro-1H-tetrazoles (AH) are reviewed in this article. Besides their synthesis and chemical behaviour, tautomerism of representatives having electron-withdrawing substituents (E, F) as well as polarization of the semicyclic double bond of the types (CH) are of interest.