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Short Paper | Regular issue | Vol 96, No. 2, 2018, pp.304-310
Published online, 25th January, 2018
DOI: 10.3987/COM-17-13848
Three New C19-Diterpenoid Alkaloids from Aconitum apetalum

Jifa Zhang, Lin Chen, and Xianli Zhou*

*School of Life Science and Engineering, Southwest Jiaotong University, NO.111, North Second Ring Road Chengdu 610031, Sichuan, China


Three new C19-diterpenoid alkaloids, named apetaldine H (1), apetaldine I (2) and apetaldine J (3), were isolated from the root of Aconitum apetalum. Their structures were elucidated by extensive spectroscopic analyses including 1D, 2D NMR, and HR-ESI-MS. Compounds (1–3) were evaluated for their cytotoxicity against the MCF-7, HepG2 and H460 human cancer cell lines.