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Paper | Special issue | Vol 97, No. 2, 2018, pp.960-967
Published online, 16th April, 2018
DOI: 10.3987/COM-18-S(T)76
Synthetic Study of Anti-Obesity Iridoid Isolated from Tabebuia avellanedae

Mitsuaki Yamashita, Shinya Hayakawa, Shuhei Hata, Honoka Murakami, Youichi Fukuda, and Akira Iida*

*School of Agriculture, Kindai University, Nakamachi, Nara 631-8505, Japan


Synthetic study toward iridoid 1 with anti-obese activity was performed by utilizing palladium-catalyzed cycloalkenylation reaction, Pd/C-catalyzed debenzylation reaction without hydrogenation and/or isomerization of alkene moiety, and the two-step, one-pot cyclization of diol as key steps.