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Paper | Regular issue | Vol 96, No. 1, 2018, pp.43-49
Published online, 21st December, 2017
DOI: 10.3987/COM-17-13810
Efficient One Pot Synthesis of Chromenonaphthyridine Derivatives by CuI/InCl3 Catalyzed Aza Diels-Alder Reaction

Pradip Kumar Maji* and Ayan Mahalanobish

*Department of Chemistry, Bidhan Chandra College , Asansol, West Bengal, India


A mild and efficient method for the synthesis of chromenonaphthyridine derivatives via domino reaction of aminopyridine and different O-propargylated salicylaldehydes using CuI/InCl3 as an efficient catalyst, refluxed in acetonitrile is reported. Mild reaction condition, operational simplicity, good to excellent yield and easy isolation of product is the silent feature of this reaction.