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■ Flavones from Cassia leschenaultiana and Their Anti-Tobacco Mosaic Virus Activity

Guang-Hui Kong, Huan-Huan Xing, Yu-Ping Wu, Zhen-Yuan Xia, Jing Li, Ling Ye, Wei-Song Kong, Xin Liu, Yan-Ping Li, Gao-Xiong Rao, Qiu-Fen Hu, Guang-Yu Yang, Yin-Ke Li,* and Xue-Mei Li*

*Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming, Jingming South Road, Chenggong New District, Kunming, Yunnan 650500, China

Abstract

Three new (1-3), together with three known flavones (4-6), were isolated from the whole plants of Cassia leschenaultiana. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds 1-4 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 3 exhibited high anti-TMV activity with inhibition rate of 48.2%. This inhibition rate is higher than that of positive control (33.8%). Compounds 1, 2, and 4 also showed potential anti-TMV activities with inhibition rates of 29.5%, 26.2%, and 27.8%, respectively.