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Obituary
Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Short Paper | Regular issue | Vol 94, No. 10, 2017, pp.1958-1964
Published online, 17th August, 2017
Published online, 17th August, 2017
DOI: 10.3987/COM-17-13784
■ Ultrasound Promoted Efficient Construction of Polycyclic-Fused Pyrazolo[4,3-c]pyridines via Domino Reaction
Ting Zhou, Dao-Lin Wang,* Jiao Xu,* Liang Yan, and Wei Ma
*College of Chemistry and Chemical Engineering, Bohai University, 19, Keji Rd., New Songshan District, Jinzhou City, Liaoning Province 121001, China
Abstract
Ultrasonic-accelerated rapid protocol for the synthesis of polycyclic-fused pyrazolo[4,3-c]pyridines via SN2/Thorpe-Ziegler/Thorpe- Guareschi domino reactions of 4-acetyl-5-bromomethyl-1-phenyl-1H-pyrazole with salicylonitriles (2-mercaptobenzonitrile or 3-cyanopyridine-2(1H)-thiones). Ultrasound‐based methodology performed better than the conventional process in rates and yields.
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