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Short Paper | Regular issue | Vol 94, No. 5, 2017, pp.957-963
Published online, 19th April, 2017
DOI: 10.3987/COM-17-13665
A Facile Synthesis of Isocoumarino[3’,4’:4,5]pyrrolo[3,2-c]coumarins from 4-Aminocoumarins and Ninhydrin

Ting Zhou, Dao-Lin Wang,* Guang-Yu Pan, and Jian-Hua Qian

*Liaoning Key Laboratory of Synthesis & Application of Functional Compound, College of Chemistry & Chemical Engineering, Bohai University, Jinzhou 121001, China


An efficient method for the synthesis of novel isocoumarino[3’,4’:4,5]pyrrolo[3,2-c]coumarins was described. The construction of this new fused heterocycles system was achieved undergo a domino reaction of 4-aminocoumarins with ninhydrin in good yields.