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Communication | Regular issue | Vol 94, No. 1, 2017, pp.55-58
Published online, 8th December, 2016
DOI: 10.3987/COM-16-13596
A Simple Approach Synthesis of Benzo[b]Pyrazolo-[3,2-h][1,6]Naphthyridin-1(2H)-Ones

Jian-Nan Yang, Dao-Lin Wang,* and Jian-Hua Qian

*Liaoning Key Laboratory of Synthesis and Application of Functional Compound, College of Chemistry & Chemical Engineering, Bohai University, Jinzhou 121001, China


A simple method for the synthesis of benzo[b]pyrazolo[3,2-h][1,6]- naphthyridin-1(2H)-ones by a tandem addition-elimination-cyclization reaction strategy from α-(dimethylaminomethylene)-2-cyanomethylquinoline-3-carboxylate and hydrazine has been developed.