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Communication | Regular issue | Vol 92, No. 12, 2016, pp.2141-2144
Published online, 11th November, 2016
DOI: 10.3987/COM-16-13590
A Facile One-Pot Synthesis of Chromeno[4,3-b][1,5]-Naphthyridines

Dong Wang, Dao-Lin Wang,* Xiao-Ce Shi, and Jian-Hua Qian

*Liaoning Key Laboratory of Synthesis and Application of Functional Compound, College of Chemistry & Chemical Engineering, Bohai University, Jinzhou 121001, China

Abstract

A simple and efficient synthesis of chromeno[4,3-b][1,5]naphthyridine derivatives were accomplished in high yields via the one-pot three-component reaction of 4-hydroxycoumarin, arylaldehyde and 3-aminopyridine in aqueous media catalyzed by sulfamic acid.