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Short Paper | Regular issue | Vol 92, No. 12, 2016, pp.2235-2243
Published online, 11th November, 2016
DOI: 10.3987/COM-16-13567
An Efficient Synthesis of Functionalized Chromeno[4,3-d]pyrazolo[3,4-b]pyridine Derivatives

Wei Lin,* Yongxiang Zheng, Yazhen Wang, and Daqing Shi*

*College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China


A series of functionalized chromeno[4,3-d]pyrazolo[3,4-b]pyridine derivatives were synthesized via one-pot three-component reaction of salicylaldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one and pyrazol-5-amines catalyzed by CuSO4 in ethanol. The structures of all synthesized were identified by their IR, 1H NMR, 13C NMR and HRMS analysis, and the structure of compound 4h was confirmed by X-ray diffraction analyses.