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Communication | Special issue | Vol 95, No. 2, 2017, pp.722-729
Published online, 19th December, 2016
DOI: 10.3987/COM-16-S(S)59
Ni-Catalyzed Three-Component Coupling of 4-Methylene-2-oxazolidinones, Alkynes, and Trimethylaluminum

Tatsuya Yamahira, Ryo Ninokata, Gen Onodera, and Masanari Kimura*

*Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan

Abstract

Ni(0) catalyzes the three-component coupling reactions of 4-methylene-2-oxazolidinones, alkynes, and trimethylaluminum accompanied by extrusion of carbon dioxide to furnish 2-methyl-3-amino-2,5-heptadiene with high regio- and stereoselectivities.