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Paper | Regular issue | Vol 91, No. 9, 2015, pp.1752-1762
Published online, 21st August, 2015
DOI: 10.3987/COM-15-13286
The Synthetic Studies of Carbazole Alkaloids

Hajime Yokoyama,* Yuzen Shoji, Takayoshi Kubo, Masahiro Miyazawa, and Yoshiro Hirai

*Department of Chemistry, Graduate School of Science and Engineering, Toyama University, Gofuku 3190, Toyama 930-8555, Japan


The carbazole alkaloids have profound biological activities and material properties. We reported that 3, 4-substituted, 3-substituted and 4-substituted carbazoles were regioselectively synthesized from indoline derivatives by means of Diels-Alder reaction in the presence or absence of Pd catalyst and attained the synthesis of natural carbazole alkaloid from 3-substituted carbazole, too.