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Short Paper | Regular issue | Vol 91, No. 7, 2015, pp.1423-1428
Published online, 29th May, 2015
DOI: 10.3987/COM-15-13228
Cu-Mediated Oxidative Dimerization of Skatole to Tryptanthrin, an Indolo[2,1-b]quinazolone Alkaloid

Tomoki Itoh, Takumi Abe, Shuhei Nakamura, and Minoru Ishikura*

*School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan


A one-pot conversion of skatole to tryptanthrin, an indolo[2,1-b]quinazoline alkaloid, was achieved by Cu-mediated oxidation.