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Short Paper | Regular issue | Vol 91, No. 3, 2015, pp.604-609
Published online, 3rd February, 2015
DOI: 10.3987/COM-14-13165
New Xanthones from Comastoma Pulmonarium and Their Anti-Tobacco Mosaic Virus Activity

Min Zhou, Kun Zhou, Ying-Liang Zhao, Neng-Jun Xiang, Tian-Dong Zhang, Cheng-Ming Zhang, Yue-De Wang, Wei Dong, Bing-Kun Ji, Li-Mei Li, Jie Lou, Gan-Peng Li,* and Qiu-Fen Hu*

*Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming, Jingming South Road, Chenggong New District, Kunming, Yunnan 650500, China

Abstract

Two new xanthones, pulmonarxanthone A (1) and pulmonarxanthone B (2), together with four known ones (3-6), were isolated from the whole plants of Comastoma pulmonarium. The structures of compounds 1–6 was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1–6 were also evaluated for their anti-tobacco mosaic virus (Anti-TMV) activity. The results showed that all the isolated compounds exhibited weak anti-TMV activity with inhibition rates in the range of 14.4–22.3%.