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Short Paper | Regular issue | Vol 89, No. 12, 2014, pp.2771-2776
Published online, 17th November, 2014
DOI: 10.3987/COM-14-13108
Flavonoids from the Leaves of Nicotiana tabacum and Their Anti-Tobacco Mosaic Virus Activity

Yinke Li, Ying-Liang Zhao, Neng-Jun Xiang, Liu Yang, Fei Wang, Guang-Yu Yang, and Zhengyin Wang*

*College of Resources and Environmental, Southwest University, NO.2 Rd Tiansheng, Beibei District,Chongqing, 400716, China


Three new flavonoids, 8-formyl-4'-hydroxy-7-methoxy-6-methyl- flavone (1), 8-formyl-4',7-dimethoxy-6-methylflavone (2), 4',6-dihydroxy- 7-methoxy-8-methoxycarbonylflavone (3) together with two known flavonoids (4 and 5) were isolated from the leaves of Nicotiana tabacum. Their structures were determined by means of HRESIMS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1-3 were tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds 1-3 exhibited inhibition rates (%) of 18.4, 22.1 and 16.4, respectively.