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Short Paper | Regular issue | Vol 89, No. 10, 2014, pp.2369-2374
Published online, 30th September, 2014
DOI: 10.3987/COM-14-13068
Isocoumarins from the Bark of Lindera caudata

Yan-Qing Ye, Cong-Fang Xia, Juan-Xia Yang, Yu-Chun Yang, Xue-Mei Gao, Gang Du, Hai-Ying Yang, Yin-Ke Li, and Qiu-Fen Hu*

*Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming, Jingming South Road, Chenggong New District, Kunming, Yunnan 650500, China


Three new isocoumarins, caudacoumarins A - C (1 - 3), together with two known isocoumarins (4 - 5) were isolated from the bark of Lindera caudata. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D- NMR techniques. Compounds 1 - 5 showed modest anti-tobacco mosaic virus (anti-TMV) activity with inhibition rate of 14.8 - 24.5%, respectively.