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Short Paper | Special issue | Vol 90, No. 1, 2015, pp.645-658
Published online, 21st May, 2014
DOI: 10.3987/COM-14-S(K)21
Diversity Oriented Approach to Oxepine Derivatives: Further Expansion via Diels‒Alder Reaction

Sambasivarao Kotha* and Rashid Ali

*Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai - 400076, India


Oxepine derivatives have been assembled via Diels‒Alder (DA) reaction as a key step and the latent dienes suitable for the DA reaction have been generated in situ from the sultine derivatives, which in turn were achieved by using commercially available rongalite. The “drug like” molecules assembled here may find useful applications in medicinal as well as bioorganic chemistry.