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Review | Special issue | Vol 90, No. 1, 2015, pp.23-40
Published online, 3rd April, 2014
DOI: 10.3987/REV-14-SR(K)1
Prenylated Acylphloroglucinols and Meroterpenoids from Hypericum Plants

Naonobu Tanaka and Jun'ichi Kobayashi*

*Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12 Nishi 6, Kita-ku, Sapporo, Hokkaido 060-0812, Japan


Hypericum plants {family Clusiaceae (APG: Hypericaceae)} are known to be a rich source of prenylated acylphloroglucinols (PAPs), some of which have attracted attention as new drug leads as well as challenging targets for total synthesis. This review covers the researches of the isolation and structure elucidation of PAPs from Hypericum plants from 2006 to 2013. Several meroterpenoids with interesting chemical structures isolated from this genus are also summarized.