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Communication | Regular issue | Vol 89, No. 2, 2014, pp.353-358
Published online, 14th January, 2014
DOI: 10.3987/COM-13-12892
Synthetic Studies of Yessotoxin: Iterative Synthesis of the AB Ring System via Pd(II)-Catalyzed Cyclization of Alcohol

Hajime Yokoyama,* Yasuhiro Kusumoto, Koshiro Sumiyoshi, Masahiro Miyazawa, and Yoshiro Hirai*

*Department of Chemistry, Graduate School of Science and Engineering, Toyama University, Gofuku 3190, Toyama 930-8555, Japan

Abstract

We report an iterative synthesis of the AB ring system of yessotoxin by using our Pd(II)-catalyzed cyclization reaction, as an approach towards a total synthesis.