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■ Palmaerins A-D, New Chlorinated and Brominated Dihydroisocoumarins with Antimicrobial and Plant Growth Regulating Activities from Discomycete Lachnum palmae

Yuka Tanabe, Takunori Matsumoto, Tsuyoshi Hosoya, Hiroyasu Sato, and Hideyuki Shigemori*

*Graduate School of Life and Environmental Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Japan

Abstract

A new chlorinated dihydroisocoumarin, palmaerin A (1), and three new brominated dihydroisocoumarins, palmaerins B (2), C (3), and D (4), were isolated from the supernatant of the culture broth containing KCl and KBr of discomycete Lachnum palmae, respectively. The structures of 1-4 were elucidated by spectroscopic data and X-ray diffraction analysis. Compounds 2 and 3 exhibited weak antibacterial activity against Bacillus subtilis and Staphylococcus aureus, while compounds 1-3 showed plant growth regulating activity against Lepidium sativum.