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Short Paper | Special issue | Vol 88, No. 1, 2014, pp.719-730
Published online, 16th July, 2013
DOI: 10.3987/COM-13-S(S)34
Synthesis of the Diazepanone-Nucleoside Core Structure of Liposidomycins and Caprazamycins Based on 7-Exo Cyclization of Epoxyamine

Hiroaki Miyaoka,* Jumpei Wada, and Etsuko Kawashima

*School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

The diazepanone-nucleoside core structure of liposidomycins and caprazamycins has been synthesized based on 7-exo cyclization of epoxyamine.