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Short Paper | Regular issue | Vol 87, No. 4, 2013, pp.877-883
Published online, 6th March, 2013
DOI: 10.3987/COM-13-12672
A Facile and Efficient Ultrasound-Assisted Synthesis of 1,3,5-Tris-arylhexahydro-1,3,5-triazine through Mannich Reaction

Xiaoxing Zhong and Guolan Dou*

*School of Safety Engineering, China University of Mining & Technology, Xuzhou 221116, China

Abstract

In this paper, we report a facile and efficient method for the synthesis of 1,3,5-tris-arylhexahydro-1,3,5-triazines by reaction of formaldehyde and aromatic amines catalyzed by triethylamine (Et3N) and assisted by ultrasound at room temperature. This method has the advantages of short reaction times, good yields and mild reaction conditions.