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Short Paper | Regular issue | Vol 87, No. 3, 2013, pp.645-655
Published online, 7th January, 2013
DOI: 10.3987/COM-12-12644
Asperelines G and H, Two New Peptaibols from the Marine-Derived Fungus Trichoderma asperellum

Li Chen,* Ping Zhong, Jian-Ru Pan, Kang-Jing Zhou, Kai Huang, Zhe-Xiang Fang, and Qi-Qing Zhang*

*Institute of Biomedical and Pharmaceutical Technology & College of Chemistry and Chemical Engineering, Fuzhou University, NO. 523, Gongye Road, Fuzhou City, 350002, China

Abstract

Two new peptaibols, asperelines G (1) and H (2), together with five known compounds, asperelines A (3), C (4), D (5), E (6), and F (7) were isolated from the marine-derived fungus Trichoderma asperellum. The structures of these compounds were determined through spectroscopic methods, X-ray diffraction analysis, and chemical derivatization. This study is the first report on asperelines with an acetylated C-terminus and a crystal structure.