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Short Paper | Regular issue | Vol 85, No. 6, 2012, pp.1447-1456
Published online, 2nd May, 2012
DOI: 10.3987/COM-12-12467
Efficient Synthesis of N-Substituted 4-Arylquinoline Derivatives Using ZnCl2 or ZrO2

Afsaneh Zonouzi,* Roghieh Mirzazadeh, Azadeh Peivandi, and Shahrzad Dehdari

*School of Chemistry, College of Science, University of Tehran, Tehran 14155-6455, Iran


N-Substituted 7,8-dihydro-7,7-dimethyl-4-arylquinolin-5(1H,4H,6H)-ones 4a-l have been reported by one-pot reaction of cinnamaldehyde derivatives, dimedone and various amines in the presence of ZnCl2 or ZrO2 in fairly high yields.