Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 85, No. 5, 2012, pp.1077-1088
Published online, 22nd March, 2012
DOI: 10.3987/COM-12-12427
Synthesis of Fluorene- and Spirobifluorene-Fused Thiophenes

Wen Yao, Qiancai Liu,* Yingbo Shi, and Jie Tang

*Department of Chemistry, East China Normal University, 500 Dongchuan Rd., Minhang, Shanghai 200241, China


A novel synthetic route to fluorene- and spirobifluorene-fused thiophenes is explored by starting with ninhydrin. The Diels-Alder cycloaddition was employed to construct the key intermediate, 2,3-bis(hydroxymethyl)-1,4-diphenyl-fluorenone, which was further converted stepwise to the target molecules. All of dihydrothiophenes and final products are confirmed by 1H NMR, 13C NMR and mass spectrometry.