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Short Paper | Regular issue | Vol 83, No. 11, 2011, pp.2601-2605
Published online, 14th September, 2011
DOI: 10.3987/COM-11-12321
Synthesis of (R)-(+)-Tanikolide, a Toxic and Antifungal δ-Lactone from the Marine Cyanobacterium Lyngbya majuscula

Keizo Matsuo,* Junko Hikita, and Keiji Nishiwaki

*Faculty of Pharmaceutical Sciences, Kinki University, 3-4-1, Kowakae, Higashi-Osaka 577-8502, Japan


(R)-(+)-Tanikolide, a brine-shrimp toxic and antifungal marine metabolite, isolated from the lipid extract of a blue green algae, cyanobacterium, Lyngbia mujuscula, was synthesized starting from (-)-quinic acid.