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Short Paper | Regular issue | Vol 83, No. 9, 2011, pp.2157-2164
Published online, 21st July, 2011
DOI: 10.3987/COM-11-12270
Aromatic Compounds from Cultured Lichen Mycobionts of Three Graphis Species

Yukiko Takenaka, Nobuo Hamada, and Takao Tanahashi*

*Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan


Spore-derived mycobionts of three lichen species, Graphis apriens, G. handelii and G. awaensis, were cultivated on a malt-yeast extract medium supplemented with 10% sucrose and their metabolites were investigated. Two new isocoumarin derivatives 1 and 2 as well as a new thiophene derivative 3 were isolated along with six known compounds. Their structures were determined by spectroscopic methods.