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Paper | Regular issue | Vol 83, No. 9, 2011, pp.2001-2010
Published online, 13th July, 2011
DOI: 10.3987/COM-11-12246
Chemistry of Nitroenamines. Part 2. Synthesis of Saturated Pyrrolo-pyrimidines and -pyrazines

Pál Scheiber,* Gábor Tóth, Mihály V. Pilipecz, Támas R. Varga, and Péter Nemes

*Department of Chemistry, School of Veterinary Medicine, Szent István University, H-1400 Budapest, P. O. Box 2, Hungary


New saturated pyrrolo-pyrimidines and pyrrolo-pyrazines were synthesized from 2-nitromethylene-pyrrolidine. Additionally, some simple aminomethylated derivatives of Mannich type were prepared. The nitro compounds were reduced into diastereomeric amines, which were separated and characterized structurally.