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Review | Regular issue | Vol 83, No. 7, 2011, pp.1489-1525
Published online, 8th April, 2011
DOI: 10.3987/REV-11-701
Synthetic Routes towards Pyrimido[1,2-a][1,3,5]triazines (Review)

Anton V. Dolzhenko*

*School of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, Western Australia 6845, Australia


The present review summarizes information on the synthetic approaches to compounds with pyrimido[1,2-a][1,3,5]triazines, 1,3,5-triazino[2,1-b]quinazolines (benzofused pyrimido[1,2-a][1,3,5]triazines), and other polyfused heterocyclic systems bearing these scaffolds. Data concerning potential applications of the pyrimido[1,2-a][1,3,5]triazines, particularly as biologically active agents, are also discussed.