HETEROCYCLES

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■ Microwave Assisted Synthesis of Fused Heterocyclic Compounds

Kumar V. Srinivasan,* Pratip K. Chaskar, Satish N. Dighe, Dhanashri S. Rane, Pranav V. Khade, and Kishor S. Jain

*Sinhgad College of Pharmacy, Vadgaon (Bk.), Pune-41, India

Abstract

Microwave assisted heating under controlled conditions has been proved beneficial for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes or even seconds. Also, microwave synthesis provides higher yields, lower cost, easy workups and greater purity as compared to lower yields, tedious workups, longer reaction times, lesser purity and termination of many by-products in the conventional thermal methods.