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Short Paper | Regular issue | Vol 83, No. 5, 2011, pp.1129-1137
Published online, 16th March, 2011
DOI: 10.3987/COM-11-12150
Antifeedant Activities of Tutin and Andrographolide Derivatives against Mythimna separata

Jun Cui, Meng-Lou Li,* Yan-Bing Zhang, and Fei-Fei Li

*College of Forestry, Northwest A & F University, Yangling, Shaanxi, 712100, China

Abstract

Nine andrographolide derivatives (A2, A3a-b, A4a-e, A5) were synthesized to study the antifeedant activities of these derivatives and tutin against Mythimna separata. Compared with tutin, the nine derivatives exhibited better antifeedant activities, and six of them showed different mortality effects. It was concluded that the potent insecticidal agents are A2 (14-deoxy-11,12-didehydro-andrographolide), A4d (15-fluorobenzylidene-14-deoxy-11,12-didehydro-andrographolide) and A4e (15-bromoacylbenzylidene-14-deoxy-11,12-didehydro-andrographolide).