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Short Paper | Regular issue | Vol 83, No. 2, 2011, pp.331-338
Published online, 27th December, 2010
DOI: 10.3987/COM-10-12078
Dowex-50W Promoted Friedländer Synthesis of Substituted Quinolines under Solvent-Free Conditions

Huey-Min Wang,* Rei-Sheu Hou, Hau-Dung Du, Iou-Jiun Kang, and Ling-Ching Chen*

*Department of Cosmetic Science, Chung Hwa University of Medical Technology, Department of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan, R.O.C.


An efficient method for the synthesis of substituted quinolines using Dowex-50W ion exchange resin as reusable eco-friendly catalyst vai Friedländer annulation under solvent-free conditions is described.