HETEROCYCLES
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Obituary
Zenichi Yoshida (1925-2023)
Zenichi Yoshida (1925-2023)
Professor. Zenichi Yoshida,
a member of the Honorary Advisors of HETEROCYCLES (1975-1998),
has passed away on May 4, 2023 at the age of 97.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
May 11, 2023
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Note | Regular issue | Vol 81, No. 7, 2010, pp.1697-1702
Published online, 14th May, 2010
Published online, 14th May, 2010
DOI: 10.3987/COM-10-11962
■ Improved Total Synthesis of Racemic Rutamarin
Ling Tong, Ruisheng Xiong, Hong Jiang, Xiangrui Jiang,* Hongbin Sun,* Hualiang Jiang, and Jingshan Shen
*Chinese Academy of Sciences, Shanghai Institute of Materia Medica, 555 Zuchongzhi Rd., Zhangjiang Hi-Tech Park, Shanghai, 201203, China
Abstract
An improved, convenient and cost-effective process, using 2,4-dihydroxybenzaldehyde 2 as starting material for (±)-rutamarin 1, is described. The overall yield of 1 is 44% in eight steps, requiring no chromatographic purification.
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