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■ Synthesis of Antioxidant Flavonoid Derivatives

Emiko Yanase, Young P. Jang, and Koji Nakanishi*

*Centennial Professor of Chemistry Emeritus, Department of Chemistry, Columbia University, 3000 Broadway, MC 3144, New York, NY 10027, U.S.A.

Abstract

Quercetin-caffeic acid and quercetin-curcumin conjugates have been synthesized as potent antioxidants to prevent age-related macular degeneration. Thus, the widely disributed plant antioxidant quercetin was linked to other plant antioxidants, caffeic acid and curucumin, to enhance its antioxidative properties.